No specific antiviral treatment is available for Zika virus disease. Treatment is generally supportive and can include rest, fluids, and use of analgesics and antipyretics. Because of similar geographic distribution and symptoms, patients with suspected Zika virus infections also should be evaluated and managed for possible Dengue or Chikungunya virus infection (CDC, May 1, 2017).
Aspirin and other non-steroidal anti-inflammatory drugs should be avoided until Dengue can be ruled out to reduce the risk of hemorrhage. People infected with Zika, Chikungunya, or Dengue virus should be protected from further mosquito exposure during the first few days of illness to prevent other mosquitoes from becoming infected and reduce the risk of local transmission (CDC, May 1, 2017).